ARK: Survival Evolved Wiki
Mutagen (Genesis Part 2)
Rare substance with aggravating and mutagentic properties. Use with caution to boost creature stats and gain access to Rockwell's Inner Sanctum.
Stack size
Added in
Spawn Command
cheat gfi Mutagen 1 0 0
cheat giveitem "Blueprint'/Game/Genesis2/CoreBlueprints/Environment/Mutagen/PrimalItemConsumable_Mutagen.PrimalItemConsumable_Mutagen'" 1 0 0
Used to craft
Crafted in
Crafting yields
6 pieces
800 × Mutagel (Genesis Part 2) Mutagel (Genesis: Part 2)

The Mutagen is a resource in the Genesis: Part 2 DLC. It enables the survivor to further evolve their existing tames, can be used to tame the Voidwyrm Voidwyrm, and used to start Terminus mission.


That looks to be the stuff that Rockwell's been using to augment and aggro all his weird creatures.

Maybe you can use it against him... You know, fight fire with fire? Bet he won't expect you to use his precious mutagen to beef up your own critters.

Can't wait to see the look on his, uh, faces when you sic those muties on him! Just be careful handling that stuff in the meantime, yeah?

~ Mutagen Record – HLN-A HLN-A


Mutagen Bulb

A Mutagen bulb as found in Rockwells innards

There are two methods of obtaining Mutagen.


6x Mutagen can be crafted with 800 Mutagel (Genesis Part 2) Mutagel (Genesis: Part 2) in the Chemistry Bench Chemistry Bench.

Mutagen Bulbs[]

Mutagen Bulbs within Rockwell's Innards biome can be harvested for 1 Mutagen and 1 Plant Species R Seed (Genesis Part 2) Plant Species R Seed (Genesis: Part 2)). A wave of multiple Summoner Summoner will be triggered upon harvesting. There are usually around 3 bulbs at a time

They respawn every 8 hours on dedicated servers, and every hour on non-dedicated servers or in single-player.

You can tell when your trip into Rockwell's Innards hunting for Bulbs has come to an end, when the white 'Mutagen' Buff disappears from the bottom right of your screen.

A successful completion of the Terminus (Genesis Part 2) Terminus (Genesis: Part 2) mission (the boss fight) grants a temporary world effect, that lowers the Bulb respawn time by 20%.


Below are all of the Mutagen Bulb locations for Genesis: Part 2. For a larger map including the other resources, see the Strategic Resource Map.

Genesis Part 2 Map


Each creature will require a certain amount of Mutagen in its inventory before it can actually be used. The tooltip for the Mutagen in the creature's inventory will show how much that creature needs so that it can be used. Once you have enough Mutagen in the creature's inventory, press E while hovering over it in the creature's inventory to apply the stat bonuses.

Mutagen can be used only once on a creature.


The stat bonus is different depending on whether the dino was tamed, or bred:

  • Tamed (only wild ancestors or clones of such tames): 5 levels are put into Health Health, Stamina Stamina, Weight Weight, and Melee Damage Melee Damage each as pre-tame levels, resulting in an increase of 20 levels overall. These levels can be inherited by the offspring.
  • Bred: 1 level is put into Health Health, Stamina Stamina, Weight Weight, and Melee Damage Melee Damage each as post-tame levels, resulting in an increase of 4 levels overall. These levels cannot be inherited by the offspring.


Required amount of Mutagen is only dependent on the species, and not the level or the bred/tamed status. Other creatures not listed here (Titans, vehicles, tames with inaccessible inventories) cannot have their stats boosted by Mutagen.

Creature Required Number
Amargasaurus Amargasaurus 24
Achatina Achatina 69
Allosaurus Allosaurus 53
Andrewsarchus Andrewsarchus 67
Anglerfish Anglerfish 18
Ankylosaurus Ankylosaurus 93
Araneo Araneo 5
Archaeopteryx Archaeopteryx 14
Argentavis Argentavis 68
Arthropluera Arthropluera 21
Astrocetus Astrocetus 99
Astrodelphis Astrodelphis 67
Baryonyx Baryonyx 52
Basilisk Basilisk 78
Basilosaurus Basilosaurus 75
Beelzebufo Beelzebufo 57
Bloodstalker Bloodstalker 36
Brontosaurus Brontosaurus 79
Bulbdog Bulbdog 6
Carbonemys Carbonemys 64
Carnotaurus Carnotaurus 27
Castoroides Castoroides 84
Chalicotherium Chalicotherium 28
Coelacanth Coelacanth 9901
Compy Compy 8
Crystal Wyvern Crystal Wyvern 85
Daeodon Daeodon 67
Deinonychus Deinonychus 24
Desmodus Desmodus 67
Dilophosaur Dilophosaur 13
Dimetrodon Dimetrodon 9
Dimorphodon Dimorphodon 29
Dinopithecus Dinopithecus 68
Diplocaulus Diplocaulus 41
Diplodocus Diplodocus 24
Dire Bear Dire Bear 66
Direwolf Direwolf 58
Dodo Dodo 2
Doedicurus Doedicurus 83
Dung Beetle Dung Beetle 90
Dunkleosteus Dunkleosteus 44
Electrophorus Electrophorus 14
Equus Equus 45
Featherlight Featherlight 6
Ferox Ferox 51
Ferox (Large) Ferox (Large) 24
Gacha Gacha 62
Gallimimus Gallimimus 36
Gasbags Gasbags 72
Giant Bee Giant Bee 9901
Giganotosaurus Giganotosaurus 99
Gigantopithecus Gigantopithecus 36
Glowtail Glowtail 6
Griffin Griffin 68
Hesperornis Hesperornis 26
Hyaenodon Hyaenodon 4
Ichthyornis Ichthyornis 31
Ichthyosaurus Ichthyosaurus 66
Iguanodon Iguanodon 33
Jerboa Jerboa 51
Kairuku Kairuku 42
Kaprosuchus Kaprosuchus 41
Karkinos Karkinos 51
Kentrosaurus Kentrosaurus 38
Lymantria Lymantria 16
Lystrosaurus Lystrosaurus 34
Maewing Maewing 32
Magmasaur Magmasaur 82
Mammoth Mammoth 62
Managarmr Managarmr 94
Manta Manta 22
Mantis Mantis 79
Megachelon Megachelon 74
Megalania Megalania 85
Megaloceros Megaloceros 37
Megalodon Megalodon 38
Megalosaurus Megalosaurus 35
Megapiranha Megapiranha 9901
Megatherium Megatherium 67
Mesopithecus Mesopithecus 24
Microraptor Microraptor 35
Morellatops Morellatops 36
Mosasaurus Mosasaurus 88
Moschops Moschops 51
Noglin Noglin 8
Onyc Onyc 3
Otter Otter 84
Oviraptor Oviraptor 60
Ovis Ovis 79
Pachy Pachy 13
Pachyrhinosaurus Pachyrhinosaurus 21
Paraceratherium Paraceratherium 66
Parasaur Parasaur 15
Pegomastax Pegomastax 29
Pelagornis Pelagornis 44
Phiomia Phiomia 48
Phoenix Phoenix 82
Plesiosaur Plesiosaur 43
Procoptodon Procoptodon 32
Pteranodon Pteranodon 79
Pulmonoscorpius Pulmonoscorpius 33
Purlovia Purlovia 33
Quetzal Quetzal 98
Raptor Raptor 24
Ravager Ravager 26
Reaper King Reaper King 93
Rex Rex 87
Rock Drake Rock Drake 82
Rock Elemental Rock Elemental 88
Roll Rat Roll Rat 46
Sabertooth Sabertooth 49
Sabertooth Salmon Sabertooth Salmon 9901
Sarco Sarco 23
Shadowmane Shadowmane 95
Shinehorn Shinehorn 6
Sinomacrops Sinomacrops 29
Snow Owl Snow Owl 46
Spino Spino 67
Stegosaurus Stegosaurus 30
Tapejara Tapejara 67
Tek Stryder Tek Stryder 9901
Terror Bird Terror Bird 37
Therizinosaur Therizinosaur 94
Titanoboa Titanoboa 9901
Titanosaur Titanosaur 9901
Thorny Dragon Thorny Dragon 49
Thylacoleo Thylacoleo 51
Triceratops Triceratops 24
Trilobite Trilobite 9901
Troodon Troodon 33
Tropeognathus Tropeognathus 67
Tusoteuthis Tusoteuthis 87
Unicorn Unicorn 45
Velonasaur Velonasaur 33
Voidwyrm Voidwyrm 82
Woolly Rhino Woolly Rhino 40
Wyvern Wyvern 82
Yutyrannus Yutyrannus 94

Video Tutorial[]


  • Contrary to the in-game description, Mutagen can be used on bred creatures.
  • It appears that mutagen nodes can despawn and the buff icon in the lower corner will not update if this happens. You can scour the entire Rockwell's Innards biome with indication that mutagen is available and find none. When you leave and re-enter the biome, you will no longer have a buff indicating that mutagen exists. This seems to be a bug, but again, further tests are required.
  • Respawn time of Mutagen Bulbs can be scaled with the AdjustableMutagenSpawnDelayMultiplier setting.


  • Torpor Torpor is not refreshed after Mutagen is applied. The player should Cryopod Cryopod their creature immediately after use.


Patch Changes
329.5 Mutagen is added to the game.
329.51 Fixed some cases where Mutagen could be fed to unintended things.
  • Fixed a bug where the Mutagen nearby buff icon would not display properly.
  • Fixed a bug where Mutagen bulbs would fall through the map in certain cases.