ARK: Survival Evolved Wiki
ARK: Survival Evolved Wiki
Mutagen (Genesis Part 2).png
Rare substance with aggravating and mutagentic properties. Use with caution to boost creature stats and gain access to Rockwell's Inner Sanctum.
Stack size
Added in
Spawn Command
cheat gfi Mutagen 1 0 0
cheat giveitem "Blueprint'/Game/Genesis2/CoreBlueprints/Environment/Mutagen/PrimalItemConsumable_Mutagen.PrimalItemConsumable_Mutagen'" 1 0 0
Used to craft
Crafted in
Crafting yields
6 pieces
800 × Mutagel (Genesis Part 2).png Mutagel (Genesis: Part 2)

The Mutagen is a resource in the Genesis: Part 2 DLC. It enables the survivor to further evolve their existing tames, can be used to tame the Voidwyrm, and used to start Terminus mission.


That looks to be the stuff that Rockwell's been using to augment and aggro all his weird creatures.

Maybe you can use it against him... You know, fight fire with fire? Bet he won't expect you to use his precious mutagen to beef up your own critters.

Can't wait to see the look on his, uh, faces when you sic those muties on him! Just be careful handling that stuff in the meantime, yeah?

~ Mutagen Record – HLN-A


A Mutagen bulb as found in Rockwells innards

There are two methods of obtaining Mutagen.


6x Mutagen can be crafted with 800 Mutagel Genesis Part 2 Icon.png in the Chemistry Bench.

Mutagen Bulbs[]

Mutagen Bulbs within Rockwell's Innards biome can be harvested for 1 Mutagen and 1 Plant Species R Seed Genesis Part 2 Icon.png). A wave of multiple Summoner will be triggered upon harvesting. There are usually around 3 bulbs at a time

They respawn every 8 hours on dedicated servers, and every hour on non-dedicated servers or in single-player.

You can tell when your trip into Rockwell's Innards hunting for Bulbs has come to an end, when the white 'Mutagen' Buff disappears from the bottom right of your screen.

A successful completion of the Terminus Genesis Part 2 Icon.png mission (the boss fight) grants a temporary world effect, that lowers the Bulb respawn time by 20%.


Below are all of the Mutagen Bulb locations for Genesis: Part 2. For a larger map including the other resources, see the Strategic Resource Map.

Genesis Part 2 Map.jpg


Each creature will require a certain amount of Mutagen in its inventory before it can actually be used. The tooltip for the Mutagen in the creature's inventory will show how much that creature needs so that it can be used. Once you have enough Mutagen in the creature's inventory, press E while hovering over it in the creature's inventory to apply the stat bonuses. Mutagen can be used only once on a creature.


The stat bonus is different depending on whether the dino was tamed, or bred:

  • Tamed (only wild ancestors or clones of such tames): 5 levels are put into Health, Stamina, Weight, and Melee Damage each as pre-tame levels, resulting in an increase of 20 levels overall. These levels can be inherited by the offspring.
  • Bred: 1 level is put into Health, Stamina, Weight, and Melee Damage each as post-tame levels, resulting in an increase of 4 levels overall. These levels cannot be inherited by the offspring.


Required amount of Mutagen is only dependent on the species, and not the level or the bred/tamed status. Other creatures not listed here (Titans, vehicles, tames with inaccessible inventories) cannot have their stats boosted by Mutagen.

Creature Required Number
Achatina 69
Allosaurus 53
Anglerfish 18
Ankylosaurus 93
Araneo 5
Archaeopteryx 14
Argentavis 68
Arthropluera 21
Astrocetus 99
Astrodelphis 67
Baryonyx 52
Basilisk 78
Basilosaurus 75
Beelzebufo 57
Bloodstalker 36
Brontosaurus 79
Bulbdog 6
Carbonemys 64
Carnotaurus 27
Castoroides 84
Chalicotherium 28
Coelacanth 9901
Compy 8
Crystal Wyvern 85
Daeodon 67
Deinonychus 24
Dilophosaur 13
Dimetrodon 9
Dimorphodon 29
Diplocaulus 41
Diplodocus 24
Dire Bear 66
Direwolf 58
Dodo 2
Doedicurus 83
Dung Beetle 90
Dunkleosteus 44
Electrophorus 14
Equus 45
Featherlight 6
Ferox 51
Ferox (Large) 24
Gacha 62
Gallimimus 36
Gasbags 72
Giant Bee 9901
Giganotosaurus 99
Gigantopithecus 36
Glowtail 6
Griffin 68
Hesperornis 26
Hyaenodon 4
Ichthyornis 31
Ichthyosaurus 66
Iguanodon 33
Jerboa 51
Kairuku 42
Kaprosuchus 41
Karkinos 51
Kentrosaurus 38
Lymantria 16
Lystrosaurus 34
Maewing 32
Magmasaur 82
Mammoth 62
Managarmr 94
Manta 22
Mantis 79
Megachelon 74
Megalania 85
Megaloceros 37
Megalodon 38
Megalosaurus 35
Megapiranha 9901
Megatherium 67
Mesopithecus 24
Microraptor 35
Morellatops 36
Mosasaurus 88
Moschops 51
Noglin 8
Onyc 3
Otter 84
Oviraptor 60
Ovis 79
Pachy 13
Pachyrhinosaurus 21
Paraceratherium 66
Parasaur 15
Pegomastax 29
Pelagornis 44
Phiomia 48
Phoenix 82
Plesiosaur 43
Procoptodon 32
Pteranodon 79
Pulmonoscorpius 33
Purlovia 33
Quetzal 98
Raptor 24
Ravager 26
Reaper King 93
Rex 87
Rock Drake 82
Rock Elemental 88
Roll Rat 46
Sabertooth 49
Sabertooth Salmon 9901
Sarco 23
Shadowmane 95
Shinehorn 6
Snow Owl 46
Spino 67
Stegosaurus 30
Tapejara 67
Tek Stryder 9901
Terror Bird 37
Therizinosaur 94
Titanoboa 9901
Titanosaur 9901
Thorny Dragon 49
Thylacoleo 51
Triceratops 24
Trilobite 9901
Troodon 33
Tropeognathus 67
Tusoteuthis 87
Unicorn 45
Velonasaur 33
Voidwyrm 82
Woolly Rhino 40
Wyvern 82
Yutyrannus 94

Video Tutorial[]


  • Contrary to the in-game description, Mutagen can be used on bred creatures.
  • Although further testing is required, it appears that mutagen nodes can despawn and the buff icon in the lower corner will not update if this happens. You can scour the entire Rockwell's Innards biome with indication that mutagen is available and find none. When you leave and re-enter the biome, you will no longer have a buff indicating that mutagen exists. This seems to be a bug, but again, further tests are required. (Tested on a dedicated server as the only member using it.)
  • Respawn time of Mutagen Bulbs can be scaled with the AdjustableMutagenSpawnDelayMultiplier setting.


  • Torpor is not refreshed after Mutagen is applied. The player should Cryopod their creature immediately after use.


Patch Changes
329.5 Mutagen is added to the game.
329.51 Fixed some cases where Mutagen could be fed to unintended things.