ARK: Survival Evolved Wiki
ARK: Survival Evolved Wiki
Mutagen (Genesis Part 2).png
Rare substance with aggravating and mutagentic properties. Use with caution to boost creature stats and gain access to Rockwell's Inner Sanctum.
Stack size
Added in
Spawn Command
cheat gfi Mutagen 1 0 0
cheat giveitem "Blueprint'/Game/Genesis2/CoreBlueprints/Environment/Mutagen/PrimalItemConsumable_Mutagen.PrimalItemConsumable_Mutagen'" 1 0 0
Used to craft
Crafted in
Crafting yields
6 pieces
800 × Mutagel (Genesis: Part 2)

The Mutagen is a resource in the Genesis: Part 2 DLC. It enables the survivor to further evolve their existing tames, can be used to tame the   Voidwyrm, and used to start Terminus mission.


That looks to be the stuff that Rockwell's been using to augment and aggro all his weird creatures.

Maybe you can use it against him... You know, fight fire with fire? Bet he won't expect you to use his precious mutagen to beef up your own critters.

Can't wait to see the look on his, uh, faces when you sic those muties on him! Just be careful handling that stuff in the meantime, yeah?

~ Mutagen Record –   HLN-A


A Mutagen bulb as found in Rockwells innards

There are two methods of obtaining Mutagen.


6x Mutagen can be crafted with 800   Mutagel (Genesis: Part 2) in the   Chemistry Bench.

Mutagen Bulbs[]

Mutagen Bulbs within Rockwell's Innards biome can be harvested for 1 Mutagen and 1   Plant Species R Seed (Genesis: Part 2)). A wave of multiple   Summoner will be triggered upon harvesting. There are usually around 3 bulbs at a time

They respawn every 8 hours on dedicated servers, and every hour on non-dedicated servers or in single-player.

You can tell when your trip into Rockwell's Innards hunting for Bulbs has come to an end, when the white 'Mutagen' Buff disappears from the bottom right of your screen.

A successful completion of the   Terminus (Genesis: Part 2) mission (the boss fight) grants a temporary world effect, that lowers the Bulb respawn time by 20%.


Below are all of the Mutagen Bulb locations for Genesis: Part 2. For a larger map including the other resources, see the Strategic Resource Map.

Genesis Part 2 Map.jpg


Each creature will require a certain amount of Mutagen in its inventory before it can actually be used. The tooltip for the Mutagen in the creature's inventory will show how much that creature needs so that it can be used. Once you have enough Mutagen in the creature's inventory, press E while hovering over it in the creature's inventory to apply the stat bonuses. Mutagen can be used only once on a creature.


The stat bonus is different depending on whether the dino was tamed, or bred:

  • Tamed (only wild ancestors or clones of such tames): 5 levels are put into   Health,   Stamina,   Weight, and   Melee Damage each as pre-tame levels, resulting in an increase of 20 levels overall. These levels can be inherited by the offspring.
  • Bred: 1 level is put into   Health,   Stamina,   Weight, and   Melee Damage each as post-tame levels, resulting in an increase of 4 levels overall. These levels cannot be inherited by the offspring.


Required amount of Mutagen is only dependent on the species, and not the level or the bred/tamed status. Other creatures not listed here (Titans, vehicles, tames with inaccessible inventories) cannot have their stats boosted by Mutagen.

Creature Required Number
  Achatina 69
  Allosaurus 53
  Anglerfish 18
  Ankylosaurus 93
  Araneo 5
  Archaeopteryx 14
  Argentavis 68
  Arthropluera 21
  Astrocetus 99
  Astrodelphis 67
  Baryonyx 52
  Basilisk 78
  Basilosaurus 75
  Beelzebufo 57
  Bloodstalker 36
  Brontosaurus 79
  Bulbdog 6
  Carbonemys 64
  Carnotaurus 27
  Castoroides 84
  Chalicotherium 28
  Coelacanth 9901
  Compy 8
  Crystal Wyvern 85
  Daeodon 67
  Deinonychus 24
  Dilophosaur 13
  Dimetrodon 9
  Dimorphodon 29
  Diplocaulus 41
  Diplodocus 24
  Dire Bear 66
  Direwolf 58
  Dodo 2
  Doedicurus 83
  Dung Beetle 90
  Dunkleosteus 44
  Electrophorus 14
  Equus 45
  Featherlight 6
  Ferox 51
  Ferox (Large) 24
  Gacha 62
  Gallimimus 36
  Gasbags 72
  Giant Bee 9901
  Giganotosaurus 99
  Gigantopithecus 36
  Glowtail 6
  Griffin 68
  Hesperornis 26
  Hyaenodon 4
  Ichthyornis 31
  Ichthyosaurus 66
  Iguanodon 33
  Jerboa 51
  Kairuku 42
  Kaprosuchus 41
  Karkinos 51
  Kentrosaurus 38
  Lymantria 16
  Lystrosaurus 34
  Maewing 32
  Magmasaur 82
  Mammoth 62
  Managarmr 94
  Manta 22
  Mantis 79
  Megachelon 74
  Megalania 85
  Megaloceros 37
  Megalodon 38
  Megalosaurus 35
  Megapiranha 9901
  Megatherium 67
  Mesopithecus 24
  Microraptor 35
  Morellatops 36
  Mosasaurus 88
  Moschops 51
  Noglin 8
  Onyc 3
  Otter 84
  Oviraptor 60
  Ovis 79
  Pachy 13
  Pachyrhinosaurus 21
  Paraceratherium 66
  Parasaur 15
  Pegomastax 29
  Pelagornis 44
  Phiomia 48
  Phoenix 82
  Plesiosaur 43
  Procoptodon 32
  Pteranodon 79
  Pulmonoscorpius 33
  Purlovia 33
  Quetzal 98
  Raptor 24
  Ravager 26
  Reaper King 93
  Rex 87
  Rock Drake 82
  Rock Elemental 88
  Roll Rat 46
  Sabertooth 49
  Sabertooth Salmon 9901
  Sarco 23
  Shadowmane 95
  Shinehorn 6
  Snow Owl 46
  Spino 67
  Stegosaurus 30
  Tapejara 67
  Tek Stryder 9901
  Terror Bird 37
  Therizinosaur 94
  Titanoboa 9901
  Titanosaur 9901
  Thorny Dragon 49
  Thylacoleo 51
  Triceratops 24
  Trilobite 9901
  Troodon 33
  Tropeognathus 67
  Tusoteuthis 87
  Unicorn 45
  Velonasaur 33
  Voidwyrm 82
  Woolly Rhino 40
  Wyvern 82
  Yutyrannus 94

Video Tutorial[]


  • Contrary to the in-game description, Mutagen can be used on bred creatures.
  • It appears that mutagen nodes can despawn and the buff icon in the lower corner will not update if this happens. You can scour the entire Rockwell's Innards biome with indication that mutagen is available and find none. When you leave and re-enter the biome, you will no longer have a buff indicating that mutagen exists. This seems to be a bug, but again, further tests are required.
  • Respawn time of Mutagen Bulbs can be scaled with the AdjustableMutagenSpawnDelayMultiplier setting.


  •   Torpor is not refreshed after Mutagen is applied. The player should   Cryopod their creature immediately after use.


Patch Changes
329.5 Mutagen is added to the game.
329.51 Fixed some cases where Mutagen could be fed to unintended things.
  • Fixed a bug where the Mutagen nearby buff icon would not display properly.
  • Fixed a bug where Mutagen bulbs would fall through the map in certain cases.